Cavalier health: diuretic study

Over at ​Search cavalierhealth.org they have published details of a diuretic study CARPODIEM study of diuretic torasemide finds it superior to furosemide in treating heart failure in MVD-affected dogs.​

"In an August 2020 article, a team of employees (Beatrice Besche, Thomas Blondel, Emilie Guillot, Catherine Garelli‐Paar) of Ceva Santé Animale, manufacturer of torasemide (brand name Isemid), along with PennVet cardiologist Mark A. Oyama, compared the diuretic to furosemide in a study of 319 MVD-affected dogs diagnosed with new onset congestive heart failure (CHF), including 52 (16.3%) cavalier King Charles spaniels. Their study is titled CARPODIEM, and their aim was to evaluate the efficacy and safety of torasemide compared to furosemide in treating CHF. They report finding that torasemide was superior to furosemide in that it required only once-daily dosing, resulting in increased owner compliance, and also that torasemide had less than half the risk of cardiac death or euthanasia or worsening of CHF than did furosemide. They emphasized that monitoring of the dogs' reactions, hydration status, renal function, and serum electrolyte concentrations should be performed when using any diuretic."